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Home / Antibodies

Anti-STAT5A (Ab-694) Antibody

SKU : BHA10917433

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y021048
Categories	Primary Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Host	Rabbit
Immunogen	The antiserum was produced against synthesized non-phosphopeptide derived from human STAT5A around the phosphorylation site of tyrosine 694 (D-G-YP-V-K).
Quantity	100 µg
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1µg/ul
Description	Specificity: STAT5A (Ab-694) antibody detects endogenous levels of total STAT5A protein.
Format	Liquid
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IHC

Description

WB: 1:500~1:1000 IHC: 1:50~1:100, WB ; IHC

Dilution

WB	1:500-1:1000~
IHC	1:50-1:100~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10917433	Y021048	100 ug	$427.50		Add to Cart

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