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Home / Primary Antibodies / Monoclonal Antibodies

Anti-SOX2

SKU : BHA15100304

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Mfr.No.	AN833-5M
Clonality	Monoclonal
Description	SOX2 or SRY related HMG BOX gene 2 is a transcription factor belongs to the SRY-related HMG-box (SOX) and it is involved in the regulation of embryonic development, determination of cell fate. SOX2 factor is critical for stem cell potency in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for Oct3/4 regulation, expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression. Structurally SOX proteins posses a single HMG box and bind to linearized DNA in a sequence-specific manner, results in the bending of DNA through large angles. Bending results in DNA helix to open, it affects binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	EP103
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:30-50

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN833-5M	AN833-5M	6 mL	$242		Add to Cart
AN833-10M	AN833-10M	100 tests - i6000	$408		Add to Cart
AY833-50D	AY833-50D	50 tests - Xmatrx	$251		Add to Cart
AY833-YCD	AY833-YCD	160 tests - Xmatrx	$646		Add to Cart
NU833-UC	NU833-UC	1ml Conc	$467		Add to Cart
NU833-5UC	NU833-5UC	0.5ml Conc	$327		Add to Cart

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