Anti-Smad7 Antibody

Mfr.No.	Y058362
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic and Nuclear
Clonality	polyclonal
Description	The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Host	Rabbit
Immunogen	Rabbit polyclonal Smad7 antibody was raised against a peptide near intermediate residues of human Smad7 protein.
Isotype	IgG
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:5,000-1:20,000
Western blot analysis: 1:500-1:1000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end use., WB ; IHC ; ELISA

Dilution

ELISA	1:5,000-1:20,000
WB	1:500-1:1000
IHC	1:50-200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10901938	Y058362	100 ul	$217.50		Add to Cart

Anti-Smad7 Antibody

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