Anti-SMAD1 Antibody

Mfr.No.	Y058305
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic and Nuclear
Clonality	polyclonal
Description	The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal SMAD1 antibody was raised against a peptide from the C terminal residues of human SMAD1 protein.
Isotype	IgG
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	TRUE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:1000-1:10000
Western blot analysis: 1:200-1:1000
Immunohistochemistry: 1:200-500
Optimal dilutions/concentrations should be determined by the end use., WB ; IHC ; ELISA

Dilution

ELISA	1:1000-1:10000
WB	1:200-1:1000
IHC	1:200-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10901505	Y058305	100 ul	$217.50		Add to Cart

Anti-SMAD1 Antibody

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