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Home / Antibodies

Anti-SLFN2/SLFN3/SLFN4(schlafen 2/schlafen 3/schlafen 4) Antibody

SKU : BHA10902121

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y050768
Categories	Primary Antibodies
Clonality	polyclonal
Description	The Schlafen (Slfn) family of genes are differentially regulated during thymocyte maturation and are preferentially expressed in the lymphoid tissues. Ectopic expression of the prototype member Slfn1 early in the T lineage profoundly alters cell growth and development. In these mice, the DP thymocytes fail to complete maturation, and, depending on the transgene dosage, the number of thymocytes is reduced to 1%-30% of normal. Furthermore, expression of the Schlafen family members in fibroblasts and thymoma cells either retards or ablates cell growth. The conceptual protein sequences deduced for each of the family members have no similarity to characterized proteins and must therefore participate in a heretofore unknown regulatory mechanism guiding both cell growth and T cell development.
Host	Rabbit
Immunogen	Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminalresidues of mouse SLFN2(schlafen 2) or to N-terminalresidues of mouse SLFN3(schlafen 3) or to N-terminal residues of mouse SLFN4(schlafen 4)
Isotype	IgG
Quantity	100 µg
Reactivity	Rat, Mouse
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.05% sodium azide.
Concentration	1µg/ul
Format	Liquid
Purity	Purified by antigen-specific affinity chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	WB, ELISA
Description	WB ; ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902121	Y050768	100 ug	$675		Add to Cart

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