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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SKAP2 Antibody Picoband®

SKU : BHA21003893

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Mfr.No.	A06280-2, A06280-2-10ug, A06280-2-Biotin, A06280-2-Cy3, A06280-2-Dylight488, A06280-2-Dylight550, A06280-2-Dylight594, A06280-2-FITC, A06280-2-HRP, A06280-2-APC, A06280-2-PE, A06280-2-iFluor647, A06280-2-carrier-free
Alternative Names	ELAV like RNA binding protein 2
Background	Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alteative splicing results in multiple transcript variants encoding different isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SKAP2 Antibody Picoband® catalog # A06280-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
Host	Rabbit
Immunogen Region	E.coli-derived human SKAP2 recombinant protein (Position: E124-E208).
Isotype	Rabbit IgG
Molecular Weight	41 kDa
Reactivity	Human, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB
Tissue Specificity	Brain; neural-specific.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O75563
Gene Id	8935
Gene Name	SKAP2
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Kouroku, Y., Soyama, A., Fujita, E., Urase, K., Tsukahara, T., Momoi, T. RA70 is a src kinase-associated protein expressed ubiquitously. Biochem. Biophys. Res. Commun. 252: 738-742, 1998. 2. Liu, J., Kang, H., Raab, M., da Silva, A. J., Kraeft, S.-K., Rudd, C. E. FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. Proc. Nat. Acad. Sci. 95: 8779-8784, 1998. 3. Marie-Cardine, A., Verhagen, A. M., Eckersko, C., Schraven, B. SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55. FEBS Lett. 435: 55-60, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003893-1	A06280-2	-	100 ug	$370		Add to Cart
BHA21003893-2	A06280-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003893-3	A06280-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003893-4	A06280-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003893-5	A06280-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003893-6	A06280-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003893-7	A06280-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003893-8	A06280-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003893-9	A06280-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003893-10	A06280-2-APC	APC	100 ug	$670		Add to Cart
BHA21003893-11	A06280-2-PE	PE	100 ug	$670		Add to Cart
BHA21003893-12	A06280-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003893-13	A06280-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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