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Home / Primary Antibodies / Polyclonal Antibodies

Anti-RPL10 Antibody Picoband®

SKU : BHA21003492

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Mfr.No.	A04190-3, A04190-3-10ug, A04190-3-Biotin, A04190-3-Cy3, A04190-3-Dylight488, A04190-3-Dylight550, A04190-3-Dylight594, A04190-3-FITC, A04190-3-HRP, A04190-3-APC, A04190-3-PE, A04190-3-iFluor647, A04190-3-carrier-free
Alternative Names	NADH dehydrogenase 4, mitochondrial
Background	60S ribosomal protein L10 is a protein that in humans is encoded by the RPL10 gene. This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RPL10 Antibody Picoband® catalog # A04190-3. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The
Host	Rabbit
Immunogen Region	E.coli-derived human RPL10 recombinant protein (Position: R3-S214).
Isotype	Rabbit IgG
Molecular Weight	23 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	NADH-ubiquinone oxidoreductase chain 4; NADH dehydrogenase subunit 4; Mtnd4; mt-Nd4; Nd4
Tissue Specificity	Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P27635
Gene Id	6134
Gene Name	RPL10
Subcellular Location	Mitochondrion membrane. Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, IF, IHC, ICC, WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug /1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Brooks, S. S., Wall, A. L., Golzio, C., Reid, D. W., Kondyles, A., Willer, J. R., Botti, C., Nicchitta, C. V., Katsanis, N., Davis, E. E. A novel ribosomopathy caused by dysfunction of RPL10 disrupts neurodevelopment and causes X-linked microcephaly in humans. Genetics 198: 723-733, 2014.<br /><br />2. Chiocchetti, A., Pakalapati, G., Duketis, E., Wiemann, S., Poustka, A., Poustka, F., Klauck, S. M. Mutation and expression analyses of the ribosomal protein gene RPL10 is an extended German sample of patients with autism spectrum disorder. Am. J. Med. Genet. 155A: 1472-1475, 2011.<br /><br />3. De Keersmaecker, K., Atak, Z. K., Li, N., Vicente, C., Patchett, S., Girardi, T., Gianfelici, V., Geerdens, E., Clappier, E., Porcu, M., Lahortiga, I., Luca, R., and 18 others. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. Nature Genet. 45: 186-190, 2013.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003492-1	A04190-3	-	100 ug	$370		Add to Cart
BHA21003492-2	A04190-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003492-3	A04190-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003492-4	A04190-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003492-5	A04190-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003492-6	A04190-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003492-7	A04190-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003492-8	A04190-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003492-9	A04190-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003492-10	A04190-3-APC	APC	100 ug	$670		Add to Cart
BHA21003492-11	A04190-3-PE	PE	100 ug	$670		Add to Cart
BHA21003492-12	A04190-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003492-13	A04190-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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