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Home / Antibodies

Anti-PPARD Antibody

SKU : BHA10903513

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y158480
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Host	Rabbit
Immunogen	Rabbit polyclonal PPARD (1) antibody was raised against a recombinate human PPARD protein 19-90aa (BC002715).
Quantity	100 µl
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% sodium azide.
Concentration	100µg/100ul
Description	Specificity: ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:200-1:1,000 Optimal dilutions/concentrations should be determined by the end use
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	WB, IHC, ELISA
Description	WB ; IHC ; ELISA

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SKU	Supplier No.	Size	Your price	Quantity
BHA10903513	Y158480	100 ul	$217.50		Add to Cart

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