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Home / Primary Antibodies / Polyclonal Antibodies

Anti-POT1 Antibody Picoband®

SKU : BHA21000682

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Mfr.No.	PB9780, PB9780-10ug, PB9780-Biotin, PB9780-Cy3, PB9780-Dylight488, PB9780-Dylight550, PB9780-Dylight594, PB9780-FITC, PB9780-HRP, PB9780-APC, PB9780-PE, PB9780-iFluor647, PB9780-carrier-free
Alternative Names	Protection of telomeres protein 1
Background	Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alteatively spliced transcript variants have been described.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-POT1 Antibody Picoband® catalog # PB9780. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. Is a component of the double-stranded telomeric DNA- binding TRF1 complex which is involved in the regulation of telomere length by ci
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human POT1, different from the related mouse sequence by eleven amino acids.
Isotype	Rabbit IgG
Molecular Weight	71 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Protection of telomeres protein 1;hPot1;POT1-like telomere end-binding protein;POT1;
Tissue Specificity	Ubiquitous. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9NUX5
Gene Id	25913
Gene Name	POT1
Subcellular Location	Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. "Entrez Gene: POT1 POT1 protection of telomeres 1 homolog (S. pombe)". 2. Baumann P, Cech TR (May 2001). "Pot1, the putative telomere end-binding protein in fission yeast and humans". Science 292 (5519): 11715. 3. Baumann P, Podell E, Cech TR (Oct 2002). "Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alteative Splicing". Mol Cell Biol 22 (22): 807987.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000682-1	PB9780	100 ug	-	$370		Add to Cart
BHA21000682-2	PB9780-10ug	10 ug	Sample	$99		Add to Cart
BHA21000682-3	PB9780-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000682-4	PB9780-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000682-5	PB9780-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000682-6	PB9780-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000682-7	PB9780-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000682-8	PB9780-FITC	100 ug	FITC	$570		Add to Cart
BHA21000682-9	PB9780-HRP	100 ug	HRP	$570		Add to Cart
BHA21000682-10	PB9780-APC	100 ug	APC	$670		Add to Cart
BHA21000682-11	PB9780-PE	100 ug	PE	$670		Add to Cart
BHA21000682-12	PB9780-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000682-13	PB9780-carrier-free	100 ug	carrier-free	$370		Add to Cart

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