Anti-Podocalyxin (PODXL) Antibody BHA10204131

Mfr.No.	5420-MSM1-P1ABX
Alternative Names	PODXL ; PDXL ; GCTM-2 ; Gp200 ; PCLP1 ; Pcx ; Podocalyxin-like protein 1
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	7q32.3
Clonality	Monoclonal
Description	Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Host	Mouse
Immunogen	A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin
Isotype	IgG1
Positive Control	HeLa, Raji, Jurkat cells, Angiosarcoma, Breast, Prostate, Liver, Pancreatic, Kidney
Reactivity	Human, Rabbit, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	O00592
Uniprot	732423
Gene Id	5420

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IP, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IP ; WB ; IHC-F

Dilution