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Home / Antibodies

Anti-PI3Kγ Antibody

BHA10917568
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 1µg/ul
Description Specificity: This Polyclonal antibody is directed against human PI3Kγprotein. The product was purified from seurm by protein A chromatography. Expect reactivity with human PI3Kγ. Cross-reactivity with PI3Kγfrom other sources has not been determined.
Relevance: Apoptosis is related to many diseases and is induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. The mammalian homologues of the key cell death gene CED-4 in C. elegans has been identified recently from human and mouse and designated Apaf-1 or apoptosis protease-activating factor 1. Cytosolic Apaf-1 forms an oligomeric complex with caspase-9 in the presence of cytochrome c and dATP, which leads to caspase-9 activation and subsequent activation of caspase-3. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains, consequently enhancing the catalytic activity of caspase-9 , leading to activation of the caspase signaling cascade and apoptosis.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/2000.
Predicted molecular weight: 126 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:2000
SKU Supplier No. Size Your price Quantity
BHA10917568 Y080013 100 ul $187.50
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