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Home / Antibodies

Anti-Phospho-MAP3K5-T918 Polyclonal Antibody

SKU : BHA13603947

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Beijing Solarbio Science & Technology Co., Ltd.

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Mfr.No.	K006190P
Alternative Names	ASK1 ; MAPKKK5 ; MEKK5
Background	Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Host	Rabbit(Rb)
Immunogen	A phospho specific peptide corresponding to residues surrounding T918 of human MAP3K5
Isotype	IgG
Molecular Weight	155kDa
Promotion	By one Solarbio antibody to get same size loading control/tag antibody for free. Click here to read more
Reactivity	Human, Mouse, Rat
Subcellular Location	Cytoplasm Endoplasmic reticulum

Swissprot	Q99683
Gene Id	4217
Gene Name	Phospho-MAP3K5-T918

Purification	Affinity purification
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Applications	WB
Dilution	WB 1:500-2000.

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SKU	Supplier No.	Size	Your price	Quantity
BHA13603947	K006190P	50µl	$278.89		Add to Cart
BHA13603947	K006190P	100µl	$356.67		Add to Cart

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