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Home / Primary Antibodies / Monoclonal Antibodies

ANTI-PERFORIN-1

SKU : BHA15100412

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BioGenex Laboratories

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Mfr.No.	AMA26-5M
Clonality	Monoclonal
Description	Perforin is a pore forming cytolytic protein. It is found in the granules of cytotoxic T lymphocytes (CTLs) and natural killer cells (NK cells) that drive to osmotic lysis of the target cells and subsequently empower granzymes to enter the target cells and stimulate apoptosis. The lytic membrane-inserting part of perforin is the MACPF domain. Perforin has structural and functional similarities to complement component 9 (C9). It has been evaluated that perforin act by creating holes in the plasma membrane which generate an influx of calcium and begins membrane repair mechanisms. These repair mechanisms bring perforin and granzymes into early endosomes. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.
Host	Mouse
Isotype	IgG2c Kappa
Reactivity	Human
Species	Mouse

Clone No	PRF1/2470
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
AMA26-5M	AMA26-5M	6 mL	$370		Add to Cart
AMA26-10M	AMA26-10M	100 tests - i6000	$625		Add to Cart
AXA26-50D	AXA26-50D	50 tests - Xmatrx	$387		Add to Cart
AXA26-YCD	AXA26-YCD	160 tests - Xmatrx	$939		Add to Cart
MUA26-UC	MUA26-UC	1ml Conc	$552		Add to Cart
MUA26-5UC	MUA26-5UC	0.5ml Conc	$390		Add to Cart

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