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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PD-L1 antibody(DM123), Rabbit mAb

SKU : BHA18100297

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DIMA Biotechnology

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Mfr.No.	DME100123
Background	This gene encodes an immune inhibitory receptor ligand that is eXpressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell actIVation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenVIronments, this interaction proVIdes an immune escape for tumor cells through cytotoXic T-cell inactIVation. EXpression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. AlternatIVe splicing results in multiple transcript variants.
Clonality	Monoclonal
Host	Rabbit
Isotype	Rabbit IgG
Reactivity	Human
Solubility	ELISA 1/5000-10000;Flow Cyt 1/100
Synonyms	PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Usage	Research use only

Form	Powder
Purification	Purified from cell culture supernatant by affinity chromatography
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Applications	ELISA,Flow Cyt

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SKU	Supplier No.	Size	Your price	Quantity
BHA18100297	DME100123	100 ug	$398		Add to Cart
BHA18100297	DME100123	10 ug	$60		Add to Cart

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