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Home / Primary Antibodies / Monoclonal Antibodies

Anti-p27 (Kip1)

SKU : BHA15100157

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BioGenex Laboratories

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Mfr.No.	AM396-5M
Clonality	Monoclonal
Description	p27kip1 (p27) is a cyclin kinase inhibitor belongs to the universal cyclin-dependent kinase inhibitor (CDKI) family. The phosphorylation on serine 10 (s10) and threonine 187 (T187) of p27/Kip1 regulates its activity. p27/Kip1 induces arrest at G1 check point and it inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4 complexes. In normal cells the expression level of p27/Kip1 is high, but level of p27/Kip1 protein expression decreases in many types of cancers, and appears to be a poor prognostic factor in several tumor models, including carcinomas of the lung, breast, colorectal, and prostate
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	DCS72
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-35

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM396-5M	AM396-5M	6 mL	$196		Add to Cart
AM396-10M	AM396-10M	100 tests - i6000	$339		Add to Cart
AX396-50D	AX396-50D	50 tests - Xmatrx	$200		Add to Cart
AX396-YCD	AX396-YCD	160 tests - Xmatrx	$594		Add to Cart
MU396-UC	MU396-UC	1ml Conc	$620		Add to Cart
MU396-5UC	MU396-5UC	0.5ml Conc	$438		Add to Cart

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