Neurotrophic tyrosine kinase receptor (NTRK) is a family of 3 proto-oncogenes including NTRK1, NTRK2, and NTRK3. NTRK gene fusions have been reported in a variety of tumor types, which are involved in biological processes such as neuronal survival, differentiation, and plasticity under physiological circumstances. Recently, the FDA has approved Entrectinib for patients with NTRK fusions, thus testing for NTRK fusions identifies patients who may be candidates for NTRK inhibitor therapy.
Host
Rabbit
Isotype
IgG, kappa (Rab)
Species
Human
Clone No
IHC707
Buffer
Tris Buffer pH7.6 with BSA, and sodium azide as preservative