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Home / Primary Antibodies

Anti-NR3C1 Antibody

SKU : BHA10903221

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058461
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
Host	Rabbit
Immunogen	Peptide
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Human
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications	IHC
Description	Optimal dilutions to be determined by researchers, IHC

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SKU	Supplier No.	Size	Your price	Quantity
BHA10903221	Y058461	100 ul	$217.50		Add to Cart

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