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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NQO1 Antibody Picoband®

SKU : BHA21004979

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Mfr.No.	A00494-2, A00494-2-10ug, A00494-2-Biotin, A00494-2-Cy3, A00494-2-Dylight488, A00494-2-Dylight550, A00494-2-Dylight594, A00494-2-FITC, A00494-2-HRP, A00494-2-APC, A00494-2-PE, A00494-2-iFluor647, A00494-2-carrier-free
Alternative Names	spleen associated tyrosine kinase
Background	NAD(P)H dehydrogenase (quinone) 1 is an enzyme that in humans is encoded by the NQO1 gene. This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. And this FAD-binding protein forms homodimers and reduces quinones to hydroquinones. In addition, this protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alteate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NQO1 Antibody Picoband® catalog # A00494-2. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive imm
Host	Rabbit
Immunogen Region	E.coli-derived human NQO1 recombinant protein (Position: M1-K274).
Isotype	Rabbit IgG
Molecular Weight	31 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk; SYK
Tissue Specificity	Widely expressed in hematopoietic cells. Expressed in neutrophils. Within the B-cell compartment, expressed from pro- and pre-B cells to plasma cells.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P15559
Gene Id	1728
Gene Name	NQO1
Subcellular Location	Cell membrane. Cytosol.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. "Entrez Gene: NQO1 NAD(P)H dehydrogenase, quinone 1". 2. Jaiswal AK (Nov 1991). "Human NAD(P)H:quinone oxidoreductase (NQO1) gene structure and induction by dioxin".Biochemistry x30 (44): 1064753. 3. Ross D, Siegel D (2004). "NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics". Methods in Enzymology382: 11544.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004979-1	A00494-2	-	100 ug	$370		Add to Cart
BHA21004979-2	A00494-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004979-3	A00494-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004979-4	A00494-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004979-5	A00494-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004979-6	A00494-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004979-7	A00494-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004979-8	A00494-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004979-9	A00494-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004979-10	A00494-2-APC	APC	100 ug	$670		Add to Cart
BHA21004979-11	A00494-2-PE	PE	100 ug	$670		Add to Cart
BHA21004979-12	A00494-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004979-13	A00494-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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