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Home / Antibodies

Anti-NOTCH4 Antibody

SKU : BHA10903426

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058338
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	Rabbit polyclonal NOTCH4 antibody was raised against a peptide from the C terminal residues of human NOTCH4.
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC, ELISA

Description

For research use only
Peptide ELISA titer: 1:5,000-1:20,000
Immunohistochemistry: 1:50-200
Optimal dilutions/concentrations should be determined by the end use, IHC ; ELISA

Dilution

ELISA	1:5,000-1:20,000
IHC	1:50-200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10903426	Y058338	100 ul	$217.50		Add to Cart

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