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Home / Antibodies

Anti-Neurogenin 3 Antibody

BHA10918253
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human Neurogenin 3 protein. The product was purified from serum by protein A chromatography. Expect reactivity with human Neurogenin 3. Cross-reactivity with Neurogenin 3 from other sources has not been determined.
Relevance: Neurogenin3 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. Neurogenin3 is also required for the specification of a common precursor of the four pancreatic endocrine cell types. In the course of mouse neurogenesis, Neurogenin2 and Neurogenin1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Neurogenin1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Neurogenin2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons. Defects in the Neurogenin3 gene are the cause of congenital malabsorptive diarrhea 4 (DIAR4), an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000~4000
Predicted molecular weight: 23 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000~4000
SKU Supplier No. Size Your price Quantity
BHA10918253 Y080078 100 ul $187.50
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