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Home / Antibodies

Anti-Neurofilament Antibody

SKU : BHA10902133

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y300125
Categories	Primary Antibodies
Clonality	monoclonal
Description	Neurofilaments comprise the exoskeleton and functionally maintain the quality of neurons. They are composed of light, medium, and heavy chains. Encoded by the NEFH gene, the heavy neurofilament protein is commonly used as a biomarker of neuronal damage. Mutations in the NEFH gene have also been associated with susceptibility to amyotrophic lateral sclerosis (ALS). The Anti-Neurofilament Antibody robustly recognizes polyphosphorylated epitopes on neurofilaments and to a much lesser extent, on other molecules such as histones and rhodopsin. The antibody also reacts with neurofibrillary tangles and plaques and cross-reacts with neurofilament medium. Thus, the Anti-Neurofilament Antibody can be used as a cell marker for neurons.
Host	Rat
Immunogen	Semi-purified neurofilaments from homogenate of rat brain.
Isotype	IgG1
Reactivity	Rat, Mouse, Human, Bovine, Chicken
Recombinant	TRUE
Regulatory	RUO

Buffer	PBS, pH 7.4 with 0.05% sodium azide
Concentration	100µg/100µl
Description	Specificity: Anti-Neurofilament Antibody recognizes Neurofilament-Heavy (NF-H) and stains sharply defined cytoplasmic filaments in neuronal cell bodies particularly axons.
Format	Liquid
Purity	The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Applications

WB, IHC

Description

WB and IHC: 1:1000~1:10000 Optimal dilutions should be calculated by the end user based on their specific application., WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:1000-1:10000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902133	Y300125	100 ul	$322.50		Add to Cart

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