The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Formulation
Liquid
Host
Mouse(Mu)
Guarantee
abm guarantees that all our Anti-Myc Tag Antibody (Mouse Monoclonal) will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen
A synthetic peptide corresponding to residues 410-419 (EQKLISEEDL) coupled to KLH.
Isotype
IgG1
Quantity
1.0 mg
Recommended Dilution
Western Blot (1:1000), Immunoprecipitation and Immunostaining (1:200). Other dilutions will need optimization by end user.
Shipping Condition
Ice Packs
Specificity
Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells.
Gene Name
Myc
Clone No
Myc.A7
Concentration
100µg/100ul
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer
PBS, pH 7.4 with 0.05% sodium azide.
Storage Condition
-20C
Description
ELISA ; ICC ; IF ; IP ; WB
No Description Available.
Reviews of Anti-Myc Tag Antibody (Mouse Monoclonal)