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Home / Antibodies

Anti-Myc (Phospho-Ser373) Antibody

SKU : BHA10916979

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y011036
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Host	Rabbit
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human Myc around the phosphorylation site of serine 373.
Quantity	100 µg
Reactivity	Rat, Mouse, Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1µg/ul
Description	Specificity: Myc (phospho-Ser373) antibody detects endogenous levels of Myc only when phosphorylated at serine 373.
Format	Liquid
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IHC

Description

IHC: 1:50~1:100, IHC

Dilution

IHC	1:50-1:100~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10916979	Y011036	100 ug	$427.50		Add to Cart

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