The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
Host
Rabbit
Immunogen
The antibody was produced against synthesized non-phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S).
Isotype
IgG
Quantity
100 µg
Reactivity
Rat, Mouse, Human
Recombinant
TRUE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
100µg/100ul
Description
Specificity: mTOR (Ab-2448) Antibody detects endogenous levels of total mTOR protein.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, IP, IHC
Description
WB: 1:500~1:1000 IHC: 1:50~1:100 IF:1:100~1:200, WB ; IP ; IHC