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Home / Primary Antibodies / Monoclonal Antibodies

Anti-MLH1

SKU : BHA15100213

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BioGenex Laboratories

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Mfr.No.	AM703-5M
Clonality	Monoclonal
Description	MutS homologue 1 (MSH1) is a member of Mutator S (MutS) DNA mismatch repair protein family. MSH1 binds to DNA mismatches to maintain the integrity of genetic information, initiate DNA repair by forming heterodimer complexes with MSH2, MSH6 and PMS2. Strand misalignment can occur during DNA replication, resulting in microsatellirte repeats, referred to as microsattelite instability (MSI). These Strand misalignments in DNA repair pathways are associated with human carcinogenesis. MLH1 gene Mutations results in increased incidence of tumors with MSI, such as in some forms of colon cancer e.g. Hereditary Non Polyposis Colon Cancer (HNPCC), a subset of sporadic carcinomas and breast cancer. Loss of expression of MLH1 has also been reported in acute lymphoblastic leukemia, endometrial carcinoma, Gastric carcinoma and ovarian carcinoma
Host	Mouse
Isotype	IgG1
Reactivity	Human
Species	Mouse

Clone No	ES05
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:10-20

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM703-5M	AM703-5M	6 mL	$310		Add to Cart
AM703-10M	AM703-10M	100 tests - i6000	$552		Add to Cart
AY703-50D	AY703-50D	50 tests - Xmatrx	$293		Add to Cart
AY703-YCD	AY703-YCD	160 tests - Xmatrx	$854		Add to Cart
MU703-UC	MU703-UC	1ml Conc	$616		Add to Cart
MU703-5UC	MU703-5UC	0.5ml Conc	$433		Add to Cart

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