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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Mesothelin-Anti-CD3 Bispecific Antibody

SKU : BHA18200130

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BPS Bioscience

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Mfr.No.	101621, 101621-1, 101621-2
Background	Bispecific antibodies (BsMab) are chimeric antibodies with the ability to bind to two antigens and are typically created for immune cell activation, interfering with signal pathways or bringing proteins together. Mesothelin is a tumor differentiation antigen present in mesothelioma, ovarian cancer, pancreatic adenocarcinoma and others. CD3 (Cluster of Differentiation 3) is present in T cells and is involved in T cell activation. The ability to bring cancer cells to T cells allows for enhanced tumor cell killing and is a valuable tool in cancer immunotherapy.
Clonality	Monoclonal
Description	Anti-Mesothelin-Anti-CD3 Bispecific Antibidy is a Knot-in-Knob antibody that recognizes human mesothelin and CD3 proteins. This human bispecific antibody has been tested for specific binding affinity to mesothelin. The recombinant antibody was affinity purified.
Formulation	8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Host	HEK293
Isotype	IgG1
Instructions for use	Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.
Molecular Weight	Heavy Chain: 49 kDa; Light Chain: 23 kDa
Species	Human
Synonyms	MSLN, MPF, SMRP
Usage	Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.
Note	Waings Avoid freeze/thaw cycles Scientific Category Immunotherapy Regulatory Status Research Use Only

Uniprot	Q13421

Format	Aqueous buffer solution.
Purity	≥90%
Shipping Temperature	-80°C
Storage	At least 6 months at -80°C.

Tested Application	Binding studies to mesothelin and CD3 in biochemical and cellular assays.

Product Manual	101621 Lot 230308-HA

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA18200130-1	101621-1	50 µg	$390		Add to Cart
BHA18200130-2	101621-2	100 µg	$535		Add to Cart

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