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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MEF2A Antibody Picoband®

SKU : BHA21000853

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Mfr.No.	PB9953, PB9953-10ug, PB9953-Biotin, PB9953-Cy3, PB9953-Dylight488, PB9953-Dylight550, PB9953-Dylight594, PB9953-FITC, PB9953-HRP, PB9953-APC, PB9953-PE, PB9953-iFluor647, PB9953-carrier-free
Alternative Names	Myocyte-specific enhancer factor 2A
Background	Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. It is mapped to 15q26. The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-MEF2A Antibody Picoband® catalog # PB9953. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA(AT) (4)TAR-3', found in numerous muscle- specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not on
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human MEF2A, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	56 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Myocyte-specific enhancer factor 2A;Serum response factor-like protein 1;MEF2A;MEF2;
Tissue Specificity	Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q02078
Gene Id	4205
Gene Name	MEF2A
Subcellular Location	Nucleus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human

Reference	1. Bhagavatula, M. R. K., Fan, C., Shen, G.-Q., Cassano, J., Plow, E. F., Topol, E. J., Wang, Q. Transcription factor MEF2A mutations in patients with coronary artery disease. Hum. Molec. Genet. 13: 3181-3188, 2004. 2. Flavell, S. W., Cowan, C. W., Kim, T.-K., Greer, P. L., Lin, Y., Paradis, S., Griffith, E. C., Hu, L. S., Chen, C., Greenberg, M. E. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311: 1008-1012, 2006. 3. Gonzalez, P., Garcia-Castro, M., Reguero, J. R., Batalla, A., Ordonez, A. G., Palop, R. L., Lozano, I., Montes, M., Alvarez, V., Coto, E. The pro279leu variant in the transcription factor MEF2A is associated with myocardial infarction. (Letter) J. Med. Genet. 43: 167-169, 2006.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000853-1	PB9953	100 ug	-	$370		Add to Cart
BHA21000853-2	PB9953-10ug	10 ug	Sample	$99		Add to Cart
BHA21000853-3	PB9953-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000853-4	PB9953-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000853-5	PB9953-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000853-6	PB9953-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000853-7	PB9953-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000853-8	PB9953-FITC	100 ug	FITC	$570		Add to Cart
BHA21000853-9	PB9953-HRP	100 ug	HRP	$570		Add to Cart
BHA21000853-10	PB9953-APC	100 ug	APC	$670		Add to Cart
BHA21000853-11	PB9953-PE	100 ug	PE	$670		Add to Cart
BHA21000853-12	PB9953-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000853-13	PB9953-carrier-free	100 ug	carrier-free	$370		Add to Cart

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