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Home / Antibodies

Anti-MDM2 (Ab-166) Antibody

SKU : BHA10917547

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y021550
Categories	Primary Antibodies
Clonality	polyclonal
Description	This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Host	Rabbit
Immunogen	The antibody was produced against synthesized non-phosphopeptide derived from human MDM2 around the phosphorylation site of Serine 166 (A-I-SP-E-T).
Isotype	IgG
Quantity	100 µg
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	Rabbit IgG in phosphate buffered saline (without Mg²+ and Ca²+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	100µg/100ul
Description	Specificity: MDM2 (Ab-166) Antibody detects endogenous levels of total MDM2 protein.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

IP, IHC

Description

IHC: 1:50~1:100 IF:1:100~1:200, IP ; IHC

Dilution

IHC	1:50-1:100~
IF	1:100-1:200~

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SKU	Supplier No.	Size	Your price	Quantity
BHA10917547	Y021550	100 ug	$427.50		Add to Cart

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