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Home / Primary Antibodies / Polyclonal Antibodies

Anti-MCM6 Antibody Picoband®

SKU : BHA21002763

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Mfr.No.	A02755-1, A02755-1-10ug, A02755-1-Biotin, A02755-1-Cy3, A02755-1-Dylight488, A02755-1-Dylight550, A02755-1-Dylight594, A02755-1-FITC, A02755-1-HRP, A02755-1-APC, A02755-1-PE, A02755-1-iFluor647, A02755-1-carrier-free
Alternative Names	Neutrophil-activating peptide 2
Background	MCM6 (Minichromosome maintenance, s. pombe, homolog of, 6) is a protein that in humans is encoded by the MCM6 gene. MCM6 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The MCM genes were originally identified in yeast defective in minichromosome maintenance and have since been shown to play roles in the progression of the cell cycle; many are cell division control genes. The MCM6 gene is mapped on 2q21.3. Mcm 6 has recently been shown to interact strongly Cdt1 at defined residues, by mutating these target residues Wei et al. observed lack of Cdt1 recruitment of Mcm2-7 to the pre-RC. An approximately 200-kb region surrounding the C/T (-13910) polymorphism in MCM6 intron 13 functioned as an enhancer of the lactase gene promoter in intestinal cell culture.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-MCM6 Antibody Picoband® catalog # A02755-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by
Host	Rabbit
Immunogen Region	E.coli-derived human MCM6 recombinant protein (Position: Q14-D821).
Isotype	Rabbit IgG
Molecular Weight	105 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Platelet basic protein; PBP; C-X-C motif chemokine 7; Leukocyte-derived growth factor; LDGF; Macrophage-derived growth factor; MDGF; Small-inducible cytokine B7; PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1; NAP-2
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q14566
Gene Id	4175
Gene Name	MCM6

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.25-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Bersaglieri, T., Sabeti, P. C., Patterson, N., Vanderploeg, T., Schaffner, S. F., Drake, J. A., Rhodes, M., Reich, D. E., Hirschho, J. N. Genetic signatures of strong recent positive selection at the lactase gene. Am. J. Hum. Genet. 74: 1111-1120, 2004.<br /><br />2. Coelho, M., Luiselli, D., Bertorelle, G., Lopes, A. I., Seixas, S., Destro-Bisol, G., Rocha, J. Microsatellite variation and evolution of human lactase persistence. Hum. Genet. 117: 329-339, 2005.<br /><br />3. Enattah, N. S., Sahi, T., Savilahti, E., Terwilliger, J. D., Peltonen, L., Jarvela, I. Identification of a variant associated with adult-type hypolactasia. Nature Genet. 30: 233-237, 2002.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002763-1	A02755-1	-	100 ug	$370		Add to Cart
BHA21002763-2	A02755-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21002763-3	A02755-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002763-4	A02755-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002763-5	A02755-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002763-6	A02755-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002763-7	A02755-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002763-8	A02755-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21002763-9	A02755-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21002763-10	A02755-1-APC	APC	100 ug	$670		Add to Cart
BHA21002763-11	A02755-1-PE	PE	100 ug	$670		Add to Cart
BHA21002763-12	A02755-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002763-13	A02755-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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