The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. (provided by RefSeq, Jul 2008)
Formulation
Liquid
Immunogen
Full length recombinant MARCKS (Myristoylated alanine rich C Kinase substrate) expressed in and purified from E. coli.
Immunogen Region
Full length recombinant MARCKS (Myristoylated alanine rich C Kinase substrate) expressed in and purified from E. coli.
Raised In
Rabbit
Shipping Condition
Ice packs
Species Reactivity
Human
Specificity
Myristoylated alanine rich C kinase substrate.
Note
Immunofluorescence: 1:250 to 1:500, for ABC or other enzyme linked immunocytochemical procedures: 1:500. Western blots: 1:1000.
Concentration
100ug/100ul
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Applications
WB, ICC/IF
Reviews of Anti-MARCKS (Rabbit Polyclonal) Antibody