Anti-LPL Antibody

Mfr.No.	G084
Categories	Primary Antibodies
Clonality	monoclonal
Description	LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]
Host	Mouse
Immunogen	Human LPL whole protein
Isotype	IgG
Quantity	100 µg
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.05% sodium azide.
Concentration	100µg/100ul
Description	Specificity: Specifically recognizes Lipoprotein Lipase (LPL) from human and bovine.
Format	Liquid
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, ELISA

Description

Western blot (1:100) and ELISA (1:200~500) in lipid metabolic research. Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion, and induction of vascular smooth muscle cell proliferation., WB ; ELISA

Dilution

WB	1:100
ELISA	1:200~500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10918476	G084	100 ug	$322.50		Add to Cart

Anti-LPL Antibody

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