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Home / Antibodies

Anti-LPA 1 Antibody

BHA10916613
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 1µg/ul
Description Specificity: This Polyclonal antibody is directed against human LPA 1 protein. The product was purified from seurm by protein A chromatography. Cross-reactivity with LPA 1 from other sources has not been determined.
Relevance: LPA 1 (also known as EDG-2) is one of four known lysophosphatidic acid (LPA) receptors (LPA 1-4).LPA1-3 are part a family of G protein-coupled receptors that share identity to the sphingosine-1-phosphate receptors (S1P 1-5 )(1). LPA 1 couples with three types of G proteins, G i/o, G q, and G 12/13 to induce a range of cellular responses including activation of phospholipase C, multiple kinases, the serum response element and cell proliferation(2,3). LPA 1 mRNA is detected a wide range of tissues and cells including brain, heart, small intestine, spleen, testis, kidney, HeLa cells, and A549 cells(4,5). Murine and human LPA 1 have 364 amino acids with an estimated molecular weight of 41 kDa(3). Us LPA 1 polyclonal antibody detects the protein from several species from 43-50 kDa, suggesting heterogeneous LPA1 post-translational modifications in distinct cells.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000.
Predicted molecular weight: 45 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000
SKU Supplier No. Size Your price Quantity
BHA10916613 Y080002 100 ul $187.50
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