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Home / Primary Antibodies / IHC Antibodies

Anti-JUN Antibody BHA11300240

SKU : BHA11300240

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Mfr.No.	BS1057
Alternative Names	JUN ; p39 ; V-jun avian sarcoma virus 17 oncogene homolog ; Proto-oncogene c-Jun ; AP1 ; Activator protein 1 ; Transcription factor AP-1
Categories	Primary Antibodies
Chromosome Location	1p32.1
Clonality	polyclonal
Description	The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 201-250 of Human c-Jun.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05412
Uniprot	P05412
Weight	; 36, 43, 48 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: c-Jun (P233) polyclonal antibody detects endogenous levels of c-Jun protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300240	BS1057	50µl	$190.44		Add to Cart
BHA11300240	BS1057	100µl	$294.44		Add to Cart

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