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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-6 IL6 Antibody Picoband®

SKU : BHA21006737

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Mfr.No.	PA1352, PA1352-10ug, PA1352-Biotin, PA1352-Cy3, PA1352-Dylight488, PA1352-Dylight550, PA1352-Dylight594, PA1352-FITC, PA1352-HRP, PA1352-APC, PA1352-PE, PA1352-iFluor647, PA1352-carrier-free
Alternative Names	Interleukin-6
Background	Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene. IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially bus or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southe blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the IL6 gene to chromosome 7p15.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-6 IL6 Antibody catalog # PA1352. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of rat IL6, different from the related mouse sequence by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Rat, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-6;IL-6;Il6;Il-6;
Tissue Specificity	Widely expressed; lower levels in brain and lung.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P20607
Gene Name	IL6
Sequence	Belongs to the histone deacetylase family. HD type 1 subfamily.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Mouse, Rat<br>

Reference	1. Ferguson-Smith AC, Chen YF, Newman MS, May LT, Sehgal PB, Ruddle FH (April 1988). "Regional localization of the interferon-beta 2/B-cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21".

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006737-1	PA1352	-	100 ug	$370		Add to Cart
BHA21006737-2	PA1352-10ug	Sample	10 ug	$99		Add to Cart
BHA21006737-3	PA1352-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006737-4	PA1352-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006737-5	PA1352-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006737-6	PA1352-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006737-7	PA1352-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006737-8	PA1352-FITC	FITC	100 ug	$570		Add to Cart
BHA21006737-9	PA1352-HRP	HRP	100 ug	$570		Add to Cart
BHA21006737-10	PA1352-APC	APC	100 ug	$670		Add to Cart
BHA21006737-11	PA1352-PE	PE	100 ug	$670		Add to Cart
BHA21006737-12	PA1352-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006737-13	PA1352-carrier-free	carrier-free	100 ug	$370		Add to Cart

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