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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Interleukin-4 IL4 Antibody Picoband®

SKU : BHA21006783

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Mfr.No.	PA1424, PA1424-10ug, PA1424-Biotin, PA1424-Cy3, PA1424-Dylight488, PA1424-Dylight550, PA1424-Dylight594, PA1424-FITC, PA1424-HRP, PA1424-APC, PA1424-PE, PA1424-iFluor647, PA1424-carrier-free
Alternative Names	Interleukin-4
Background	Interleukin-4 (IL-4), also knowns as a B-cell stimulatory factor1 (BSF1), is an immunomodulatory cytokine, which can inhibit the growth of tumour cells.1 The human cDNA contains a single open reading frame encoding a protein of 153 amino acids, including a putative signal peptide. IL-4 may act as an autocrine growth factor in pancreatic cancer cells and also give rise to the possibility that cancer-derived IL-4 may suppress cancer-ed immunosurveillance in vivo in addition to its growth-promoting effects, thereby facilitating pancreatic tumor growth and metastasis.1 The mouse and human genes and their protein products show structural and functional similarities. The human IL-4 gene, which occurs as a single copy in the haploid genome, is mapped on chromosome 5.2 The standard product used in this kit is recombinant human IL-4, consisting of 130 amino acids with the molecular mass of 14KDa.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Interleukin-4 IL4 Antibody catalog # PA1424. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface express
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human IL-4.
Isotype	Rabbit IgG
Molecular Weight	15 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Interleukin-4;IL-4;B-cell stimulatory factor 1;BSF-1;Binetrakin;Lymphocyte stimulatory factor 1;Pitrakinra;IL4;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P05112
Gene Name	IL4
Sequence	Belongs to the IL-4/IL-13 family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br>

Reference	1. Prokopchuk, O.; Liu, Y.; Henne-Bruns, D.; Komann, M. Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. Br J Cancer.2005 Mar 14;92(5):921-8.<br /><br />2. Arai, N.; Nomura, D.; Villaret, D.; DeWaal Malefijt, R.; Seiki, M.; Yoshida, M.; Minoshima, S.; Fukuyama, R.; Maekawa, M.; Kudoh, J.; Shimizu, N.; Yokota, K.; Abe, E.; Yokota, T.; Takebe, Y.; Arai, K. Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression. J. Immun. 142: 274-282, 1989.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006783-1	PA1424	-	100 ug	$370		Add to Cart
BHA21006783-2	PA1424-10ug	Sample	10 ug	$99		Add to Cart
BHA21006783-3	PA1424-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006783-4	PA1424-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006783-5	PA1424-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006783-6	PA1424-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006783-7	PA1424-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006783-8	PA1424-FITC	FITC	100 ug	$570		Add to Cart
BHA21006783-9	PA1424-HRP	HRP	100 ug	$570		Add to Cart
BHA21006783-10	PA1424-APC	APC	100 ug	$670		Add to Cart
BHA21006783-11	PA1424-PE	PE	100 ug	$670		Add to Cart
BHA21006783-12	PA1424-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006783-13	PA1424-carrier-free	carrier-free	100 ug	$370		Add to Cart

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