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Home / Primary Antibodies

Anti-IL-6R Antibody

SKU : BHA10902271

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y058140
Categories	Primary Antibodies
Cellular Localization	Cell membrane; basolateral cell membrane; single pass type I membrane protein.
Clonality	polyclonal
Description	Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported
Host	Rabbit
Immunogen	Synthetic peptide conjugated to KLH
Isotype	IgG
Quantity	100 µl
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Shipping Condition	Ice Packs

Buffer	PBS, pH 7.4 with 0.02% Sodium Azide
Concentration	100µg/100ul
Description	Specificity: Not yet tested in other species.
Format	Liquid
Purity	Affinity purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition	-20C

Applications

WB, ELISA

Description

For research use only
Peptide ELISA titer: 1:40,000-1:80,000
Western blot analysis: 1:200-500
Optimal dilutions/concentrations should be determined by the end use., WB ; ELISA

Dilution

ELISA	1:40,000-1:80,000
WB	1:200-500

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SKU	Supplier No.	Size	Your price	Quantity
BHA10902271	Y058140	100 ul	$217.50		Add to Cart

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