Formyl peptide receptors (FPR) are a family of G-protein-coupled receptors of mammalian phagocytic cells are involved in antibacterial host defense and inflammation. Activating these receptors can mediate neutrophil chemotaxis, production of reactive oxygen species and stimulate degranulation of neutrophils. NFPRb (NFPR2) can be employed in the study of inflammation sites where the accumulation, activation and control of neutrophils is partly driven by the binding of N-formyl peptides to N-formyl peptide chemoattractant receptors (FPRs).
Formulation
Liquid
Immunogen
Expressed and purified a hexa-histidine-tagged recombinant FPR1 (rHis-FPR1) in Spodoptera frugiperda (Sf9)
Immunogen Region
Expressed and purified a hexa-histidine-tagged recombinant FPR1 (rHis-FPR1) in Spodoptera frugiperda (Sf9)
Isotype
IgG1
Raised In
Mouse
Shipping Condition
Ice packs
Specificity
Region of FPR1 containing the cytoplasmic c-terminal tail residues 338-STLPSAEVELQAK-350
Note
Western Blot, Immunoprecipitation, Immunofluorescence and Immunopurification
Clone No
NFPRb
Storage
This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.