Capsid protein p24 ; Human immunodeficiency virus type 1 p24 ; HIV1gp1 ; HIV-1 Gag p24
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
monoclonal
Description
Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.
Host
Mouse
Immunogen
Recombinant HIV-1 Gag p24 protein
Positive Control
HIV-1 infected cells or tissues.
Reactivity
HIV Type 1
Recombinant
FALSE
Regulatory
RUO
Swissprot
Not Applicable
Uniprot
Not Applicable
Gene Id
Not Applicable
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA at 1.0mg/ml
Applications
ELISA, IHC(af), IF
Description
Optimal dilution for a specific application should be determined., ELISA ; IHC(af) ; IF
Dilution
ELISA
For coating, order Ab without BSA
IHC(af)
0.5-1μg/ml for 30 min
IF
0.5-1μg/ml
Reviews of Anti-Human Immunodeficiency Virus Type-1 p24 (HIV1-p24) Antibody BHA10207192