This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Formulation
Liquid
Host
Rabbit(Rb)
Guarantee
abm guarantees that all our Anti Human DOCK8 Polyclonal Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen
Recombinant Protein
Isotype
IgG
Quantity
100μl
Recommended Dilution
ELISA 1:1,000~100,000 Western blotting 1:100~1,000
Shipping Condition
Ice Packs
Species Reactivity
Human
Gene Name
DOCK8
Clone No
Polyclonal
Concentration
1µg/ul
Purity
Antigen Affinity Purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.