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Home / Antibodies

Anti-Human ASK-1 phospho specific pS83 Antibody

SKU : BHA10920815

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Y050390
Categories	Primary Antibodies ; Phospho Antibodies
Clonality	polyclonal
Description	ASK-1 (apoptosis signal-regulating kinase 1 - also referred to as MEK Kinase-5 or MAPKKK5) is a novelserine/threonine MAP kinase kinase kinase (MAPKKK) component of the mitogen -activated protein (MAP) cascade that is activatedin response to extracellular stimuli by cytokines, growth factors and environmental stresses and other factors. Overexpression ofASK-1 induces apoptotic cell death. ASK-1 is expressed in a variety of human and mouse tissues. The overall amino acid sequenceidentity between the mouse and human ASK1 is 91.9%. ASK-1 interacts with CDKN1A (also known as p21, WAF1, CIP1). Pleaserefer to the reference list at the end of this document for further information.
Formulation	Liquid
Host	Rabbit(Rb)
Guarantee	abm guarantees that all our Anti-Human ASK-1 phospho specific pS83 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen	This purified antibody was prepared from rabbit serum after repeated immunizations with a KLH conjugated peptidecorresponding to amino acids 76-87 of human ASK-1 protein.
Isotype	IgG
Quantity	100 μg
Recommended Dilution	This phospho specific polyclonal antibody reacts human pS83 ASK1 and shows minimal reactivity by westernblot, ELISA and competitive ELISA with non-phosphorylated ASK1. Although not tested, this antibody is likely functional in RIA,immunohistochemistry and immunoprecipitation.
Shipping Condition	Ice Packs
Species Reactivity	Human
Specificity	This product is an IgG fraction antibody purified from antiserum by a multi-step process which includesdelipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. No reaction was observed with ASK-1from mouse sources. Reactivity with the kinase from other sources has not been determined.

Gene Name	Human ASK-1
Clone No	Polyclonal

Concentration	1µg/ul
Purity	Purified
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Buffer	PBS, pH 7.4 with 0.05% sodium azide.
Storage Condition	-20C

Description	ELISA ; WB

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10920815	Y050390	100 ug	$1162.50		Add to Cart

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