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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Histone deacetylase 2 HDAC2 Antibody Picoband®

SKU : BHA21006735

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Mfr.No.	PA1350, PA1350-10ug, PA1350-Biotin, PA1350-Cy3, PA1350-Dylight488, PA1350-Dylight550, PA1350-Dylight594, PA1350-FITC, PA1350-HRP, PA1350-APC, PA1350-PE, PA1350-iFluor647, PA1350-carrier-free
Alternative Names	Histone deacetylase 2
Background	Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene. This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Betz et al. (1998) performed PCR using HDAC2-specific primers to screen a somatic cell hybrid mapping panel. They mapped the HDAC2 gene to human chromosome 6q21, a region of the genome altered in some cancers, including retinoblastoma.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Histone deacetylase 2 HDAC2 Antibody catalog # PA1350. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progr
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human HDAC2, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Rat, Mouse, Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Histone deacetylase 2;HD2;3.5.1.98;HDAC2;
Tissue Specificity	Widely expressed; lower levels in brain and lung.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q92769
Gene Name	HDAC2
Sequence	Belongs to the histone deacetylase family. HD type 1 subfamily.
Subcellular Location	Nucleus . Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Betz R, Gray SG, Ekstrom C, Larsson C, Ekstrom TJ (Dec 1998). "Human histone deacetylase 2, HDAC2 (Human RPD3), is localized to 6q21 by radiation hybrid mapping".

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006735-1	PA1350	-	100 ug	$370		Add to Cart
BHA21006735-2	PA1350-10ug	Sample	10 ug	$99		Add to Cart
BHA21006735-3	PA1350-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006735-4	PA1350-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006735-5	PA1350-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006735-6	PA1350-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006735-7	PA1350-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006735-8	PA1350-FITC	FITC	100 ug	$570		Add to Cart
BHA21006735-9	PA1350-HRP	HRP	100 ug	$570		Add to Cart
BHA21006735-10	PA1350-APC	APC	100 ug	$670		Add to Cart
BHA21006735-11	PA1350-PE	PE	100 ug	$670		Add to Cart
BHA21006735-12	PA1350-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006735-13	PA1350-carrier-free	carrier-free	100 ug	$370		Add to Cart

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