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Home / Primary Antibodies

Anti-HIF-1ß Antibody

BHA10917243
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Buffer PBS, pH 7.4 with 0.02% sodium azide.
Concentration 100µg/100ul
Description Specificity: This Polyclonal antibody is directed against human HIF-1βprotein. The product was purified from serum by protein A chromatography. Expect reactivity with human HIF-1β. Cross-reactivity with HIF-1β from other sources has not been determined.
Relevance: Oxygen availability plays a major role in the regulation of expression of many different genes including erythropoietin, nitric oxide synthase (NOS), heme oxygenase 1 (HO-1), glucose transporters and vascular growth factors necessary for the maintenance of homeostasis in hypoxic conditions. Hypoxia-inducible factor 1 alpha (HIF1 alpha) has been identified as a bHLH-PAS family member that is instrumental in the oxygen-dependent regulation of these genes. HIF1 alpha rapidly accumulates in the nucleus upon exposure to hypoxic conditions where it heterodimerises with the aryl hydrocarbon nuclear receptor translocator ARNT (also referred to as HIF1 beta). Heterodimerisation promotes efficient DNA binding.
Format Liquid
Purity Affinity purified
Storage This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition -20C
Applications WB
Description Recommended dilutions
WB: 1/1000~4000
Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user., WB
Dilution

WB1:1000~4000
SKU Supplier No. Size Your price Quantity
BHA10917243 Y080080 100 ul $187.50
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