Cytoplasmic, membrane associated and mitochondrial
Clonality
polyclonal
Host
Rabbit
Immunogen
Synthetic peptide conjugated to KLH
Isotype
IgG
Quantity
100 µl
Reactivity
Mouse, Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Concentration
100µg/100ul
Description
Specificity: HCLS1 antibody detects endogenous levels of HCLS1 protein. Not tested with other proteinsRelevance: Hematopoietic cell specific Lyn substrate 1 (HCLS1) is an intracellular protein involved in the signal transduction pathways in B and T lymphocytes. HCLS1 Tyr phosphorylation catalyzed by Syk and Lyn plays a crucial role in the translocation of the protein to the membrane and is involved in the cytoskeleton rearrangement triggered by thrombin in human platelets. The gene is a substrate for caspase cleavage during apoptosis.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, IHC, ELISA
Description
For research use onlyPeptide ELISA titer: 1:40,000-1:80,000Western blot analysis: 1:200-1:1,000Immunohistochemistry: 1:50-200Optimal dilutions/concentrations should be determined by the end use, WB ; IHC ; ELISA