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Home / Primary Antibodies / Monoclonal Antibodies

Anti-GPX1 Antibody Picoband® (monoclonal, 8B10)

SKU : BHA21002121

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Mfr.No.	M01019-2, M01019-2-10ug, M01019-2-Biotin, M01019-2-Cy3, M01019-2-Dylight488, M01019-2-Dylight550, M01019-2-Dylight594, M01019-2-FITC, M01019-2-HRP, M01019-2-APC, M01019-2-PE, M01019-2-iFluor647, M01019-2-carrier-free
Alternative Names	glutathione peroxidase 1
Background	Glutathione peroxidase 1, also known as, GPX-1 is an enzyme that in humans is encoded by the GPX1 gene. It is mapped to 3p21.31. This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.
Clonality	Monoclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GPX1 Antibody Picoband® (monoclonal, 8B10) catalog # M01019-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Protects the hemoglobin in erythrocytes from oxidative breakdown.
Host	Mouse
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human GPX1, different from the related mouse sequence by six amino acids and from the related rat sequence by five amino acids.
Isotype	Mouse IgG2b
Molecular Weight	22 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Glutathione peroxidase 1; GPx-1; GSHPx-1; Cellular glutathione peroxidase; GPX1
Tissue Specificity	Higher expression in skeletal muscle and heart and to a lesser extent in liver, brain, placenta, lung, kidney and pancreas.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P07203
Gene Id	2876
Gene Name	GPX1
Clone No	Clone: 8B10
Subcellular Location	Cytoplasm

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 5ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br>

Reference	1.Kiss C, Li J, Szeles A, Gizatullin RZ, Kashuba VI, Lushnikova T, Protopopov AI, Kelve M, Kiss H, Kholodnyuk ID, Imreh S, Klein G, Zabarovsky ER (Jun 1998). "Assignment of the ARHA and GPX1 genes to human chromosome bands 3p21.3 by in situ hybridization and with somatic cell hybrids". Cytogenet Cell Genet 79 (34): 22830.<br /><br />2."Entrez Gene: GPX1 glutathione peroxidase 1"

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002121-1	M01019-2	-	100 ug	$370		Add to Cart
BHA21002121-2	M01019-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002121-3	M01019-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002121-4	M01019-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002121-5	M01019-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002121-6	M01019-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002121-7	M01019-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002121-8	M01019-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002121-9	M01019-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002121-10	M01019-2-APC	APC	100 ug	$670		Add to Cart
BHA21002121-11	M01019-2-PE	PE	100 ug	$670		Add to Cart
BHA21002121-12	M01019-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002121-13	M01019-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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