Anti-gp100 / Melanosome / PMEL17 / SILV Antibody BHA10204936

Mfr.No.	6490-MSM4-P1ABX
Alternative Names	95kDa melanocyte-specific secreted glycoprotein ; M-beta ; Melanocyte lineage specific antigen GP100 ; Melanocyte protein Pmel 17 ; Melanoma associated ME20 antigen ; Melanosomal matrix protein17 ; p100 ; p26 ; PMEL17 ; Premelanosome protein
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	12q13.2
Clonality	Monoclonal
Description	By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
Host	Mouse
Immunogen	Extract of pigmented melanoma metastases from lymph nodes (HMB45); Recombinant human SILV protein (PMEL/783)
Isotype	IgG
Positive Control	SK-MEL-28 cells or Melanoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P40967
Uniprot	95972
Gene Id	6490

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1.0μg/ml for 30 minutes at RT

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204936	6490-MSM4-P1ABX	100µg	$393.20		Add to Cart

Anti-gp100 / Melanosome / PMEL17 / SILV Antibody BHA10204936

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