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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Glutathione S-Transferase Pi (GST Pi)

SKU : BHA15100092

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BioGenex Laboratories

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Mfr.No.	AR249-5R
Clonality	Polyclonal
Description	Glutathione S-transferases (GSTs) are a group of enzymes centrally involved with drug metabolism and detoxification. Because of their role in detoxification, they have been implicated in anticancer drug sensitivity and resistance. The glutathione S-transferases (GSTs) are a multigene family of isoenzymes which catalyse the conjugation of glutathione to electrophilic substrates. All eukaryotic species possess multiple cytosolic and membrane-bound GST isoenzymes, each of which displays distinct catalytic as well as noncatalytic binding properties. The cytosolic enzymes are encoded by at least five distantly related gene families (designated class alpha, mu, pi, sigma, and theta GST), whereas the membrane-bound enzymes, microsomal GST and leukotriene C4 synthetase, are encoded by single genes and both have arisen separately from the soluble GST. The pi class is found in a wide variety of normal human tissues, including kidney collecting ducts and distal convoluted tubules; urinary, digestive tract and digestive gland epithelium; Schwann and glial cells; lymph node germinal centers; and the endothelium and smooth muscle of blood vessels. In addition, it is also found in multiple structures in the reproductive and endocrine systems, among which are the adrenal cortex and medulla, thyroid follicle cells, ovarian follicles, breast acinar and ductal epithelium, testis epididymis and prostate glandular epithelium and smooth muscle. It is thought that the concentration of GST isoenzymes may play an important role both in the susceptibility of normal tissue to chemotoxins and carcinogens
Host	Rabbit
Isotype	NA
Reactivity	Human
Species	Rabbit

Clone No	Polyclonal
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AR249-5R	AR249-5R	6 mL	$179		Add to Cart
AR249-10R	AR249-10R	100 tests - i6000	$310		Add to Cart
AW249-50D	AW249-50D	50 tests - Xmatrx	$183		Add to Cart
AW249-YCD	AW249-YCD	160 tests - Xmatrx	$526		Add to Cart
PU249-UP	PU249-UP	1ml Conc	$246		Add to Cart
PU249-5UP	PU249-5UP	0.5ml Conc	$174		Add to Cart

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