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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Glutamine Synthetase Antibody

SKU : BHA14800136

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GenomeMe Lab Inc

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Mfr.No.	IHC586-7
Clonality	Monoclonal
Description	Glutamine Synthetase (GS-6 or GS) catalyzes the conversion of glutamate and ammonia to glutamine in the liver, and is expressed in pericentral hepatocytes, but not in periportal hepatocytes or in the mid-zonal hepatocytes. Anti-Glutamine Synthetase is useful in some hepatocellular carcinomas and many high grade dysplastic nodules, and therefore may be useful in recognizing these cases. A panel of antibodies against HSP70 (heat shock protein 70), GPC3, and glutamine synthetase is useful for differentiating dysplastic from early malignant hepatocellular nodules in cirrhosis. GS staining of hepatocellular lesions is useful for the differential diagnosis of focal nodular hyperplasia (FNH), hepatic adenoma (HCA), dysplastic nodules, and low grade hepatocellular carcinoma. FNH produces a “map-like” pattern when stained with Anti-Glutamine Synthetase. Conversely, HCA can stain negatively, produce border staining, or stain around the tumour veins.
Host	Mouse
Isotype	IgG2a
Species	Human

Clone No	IHC586

Buffer	Tris Buffer pH7.6 with BSA, and sodium azide as preservative
Storage	-20 degrees Celsius

Applications	WB, IHC, ELISA
Dilution	1:200

Product Manual	MSDS

No Description Available.

GeneAbﾙ Glutamine Synthetase [IHC586] on Liver Cancer

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SKU	Supplier No.	Size	Your price	Quantity
BHA14800136	IHC586-7	7ml RTU Predilute	$160		Add to Cart

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