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Home / Primary Antibodies / Polyclonal Antibodies

Anti-GCHFR Antibody Picoband®

SKU : BHA21003050

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Mfr.No.	A08185-3, A08185-3-10ug, A08185-3-Biotin, A08185-3-Cy3, A08185-3-Dylight488, A08185-3-Dylight550, A08185-3-Dylight594, A08185-3-FITC, A08185-3-HRP, A08185-3-APC, A08185-3-PE, A08185-3-iFluor647, A08185-3-carrier-free
Alternative Names	ZFP42 zinc finger protein
Background	GTP cyclohydrolase 1 feedback regulatory protein is an enzyme that in humans is encoded by the GCHFR gene. GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-GCHFR Antibody Picoband® catalog # A08185-3. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-ren
Host	Rabbit
Immunogen Region	E.coli-derived human GCHFR recombinant protein (Position: P2-E84).
Isotype	Rabbit IgG
Molecular Weight	12 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Zinc finger protein 42 homolog; Zfp-42; Reduced expression protein 1; REX-1; hREX-1; Zinc finger protein 754; ZFP42; REX1; ZNF754
Tissue Specificity	Expressed in kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells (at protein level). Expressed in malignant kidney and several carcinoma cell lines (at protein level). Expressed in embryonic stem cells, kidney, epidermal keratinocytes, prostate epithelial cells, bronchial and small airway lung epithelial cells. Expressed in embryonal carcinomas, seminomas, malignant kidney and several carcinoma cell lines.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.005mg NaN3.

Uniprot	P30047
Gene Id	2644
Gene Name	GCHFR
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.25ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Milstien, S., Jaffe, H., Kowlessur, D., Bonner, T. I. Purification and cloning of the GTP cyclohydrolase I feedback regulatory protein, GFRP. J. Biol. Chem. 271: 19743-19751, 1996

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003050-1	A08185-3	-	100 ug	$370		Add to Cart
BHA21003050-2	A08185-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21003050-3	A08185-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003050-4	A08185-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003050-5	A08185-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003050-6	A08185-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003050-7	A08185-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003050-8	A08185-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21003050-9	A08185-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21003050-10	A08185-3-APC	APC	100 ug	$670		Add to Cart
BHA21003050-11	A08185-3-PE	PE	100 ug	$670		Add to Cart
BHA21003050-12	A08185-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003050-13	A08185-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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