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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Gamma-Synuclein Antibody

SKU : BHA21301187

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Alomone Labs

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Mfr.No.	APZ-037, APZ-037-CF_0.2 ml, APZ-037_0.2 ml, APZ-037_25 mcl, APZ-037_50 mcl
Lead Time	1-2 Business Days
Immunogen Species	Rat
Background	gamma-synuclein is a 127 amino acids protein that belongs to the synuclein family of proteins. Synucleins are natively unfolded proteins, i.e. they have no secondary or tertiary structure in solution and hence these proteins are heat stable. The unusual biophysical properties of synucleins are rooted in their characteristic primary sequence that includes a highly conserved N-terminal domain with an 11- residue repeat and a less conserved acidic C-terminal domain that contains many proline residues1.Mammalian gamma-synuclein, encoded by BCSG1 (breast cancer specific gene 1), was discovered in a screen for breast cancer markers2. It is expressed in the peripheral nervous system in primary sensory neurons, sympathetic neurons, and motor neurons. It is also detected in the brain3, olfactory epithelium and breast/ovarian tumors4. Indeed, exogenous expression of this protein increases the invasive and metastatic potential of breast tumors5.The roles of synucleins are not fully elucidated but this group of conserved and unusual proteins contributes to diverse disease processes spanning neurodegenerative disease and cancer and hence, studying the synucleins specific cellular activity is very tempting and promising.
Clonality	Polyclonal
Description	Anti-Gamma-Synuclein Antibody (#APZ-037) is a highly specific antibody directed against an epitope of the rat protein. It can be used in western blot analysis. It has been designed to recognize gamma-Synuclein from mouse and rat samples. The antibody will not recognize the protein from human samples.
Formulation	PBS pH7.4
Host	Rabbit
Immunogen Region	C-terminus
Isotype	Rabbit IgG
Reactivity	Rat, Mouse
Reconstitution	0.2 ml double distilled water (DDW).
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Synonyms	gamma-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG
UNSPSC Code	41116161
Note	Homology: Mouse - identical Peptide confirmation: Confirmed by amino acid analysis and mass spectrometry Negative Control: BLP-PZ037 Specifictiy: SNCG AB Specifictiy: Not recommended for use with human samples. Is Toxin: No Standard quality control of each lot: Western blot analysis Antigen preadsorption control: 1 ug peptide per 1 ug antibody

Accession Number	O76070
Gene Id	64347
Target	gamma-Synuclein, Breast Cancer-Specific Gene 1 Protein, BCSG1, Persyn, Synoretin, SNCG
Sequence	(C)RKEDLEPPAQDQE, corresponding to amino acid residues 96 - 108 of rat gamma-Synuclein

Conjugates	Unconjugated

Concentration	1 mg/ml
Form	Lyophilized powder. Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4.
Preservative	No Preservative
Purity	Affinity purified on immobilized antigen.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Storage Before Reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Applications	IF, IHC, WB
Dilution	1:200

Product Manual	SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA21301187-1	APZ-037-CF_0.2 ml	0.2 ml(Carrier Free)	$994		Add to Cart
BHA21301187-2	APZ-037_0.2 ml	0.2 ml	$795		Add to Cart
BHA21301187-3	APZ-037_25 mcl	25 mcl	$597		Add to Cart
BHA21301187-4	APZ-037_50 mcl	50 mcl	$697		Add to Cart

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