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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Galectin 1/LGALS1 Antibody Picoband®

SKU : BHA21006781

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Mfr.No.	PA1422, PA1422-10ug, PA1422-Biotin, PA1422-Cy3, PA1422-Dylight488, PA1422-Dylight550, PA1422-Dylight594, PA1422-FITC, PA1422-HRP, PA1422-APC, PA1422-PE, PA1422-iFluor647, PA1422-carrier-free
Alternative Names	Galectin-1
Background	Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. Galectins belong to a family of related beta-galactoside-binding lectins, also referred to as S-type or S-Lac lectins. Its gene is mapped to 22q12-q13. Galectin-1 was expressed in a subset of slowly dividing subventricular zone astrocytes, which included the neural stem cells. It has been considered as an autocrine negative growth factor that regulates cell proliferation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Galectin 1/LGALS1 Antibody catalog # PA1422. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell a
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Galectin 1, different from the related rat and mouse sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	15 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Galectin-1;Gal-1;14 kDa laminin-binding protein;HLBP14;14 kDa lectin;Beta-galactoside-binding lectin L-14-I;Galaptin;HBL;HPL;Lactose-binding lectin 1;Lectin galactoside-binding soluble 1;Putative MAPK-activating protein PM12;S-Lac lectin 1;LGALS1;
Tissue Specificity	Expressed in placenta, mateal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.01mg NaN3.

Uniprot	P09382
Gene Name	LGALS1
Sequence	Contains 1 galectin domain.
Subcellular Location	Secreted, extracellular space, extracellular matrix .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Gitt MA, Barondes SH (February 1991). "Genomic sequence and organization of two members of a human lectin gene family". Biochemistry 30 (1): 829. <br /><br />2. Gauthier L, Rossi B, Roux F, Termine E, Schiff C (October 2002). "Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering". Proc Natl Acad Sci U S A 99 (20): 130149. <br /><br />3. Mehrabian, M., Gitt, M. A., Sparkes, R. S., Leffler, H., Barondes, S. H., Lusis, A. J.Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13.Genomics15: 418-420, 1993.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006781-1	PA1422	-	100 ug	$370		Add to Cart
BHA21006781-2	PA1422-10ug	Sample	10 ug	$99		Add to Cart
BHA21006781-3	PA1422-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006781-4	PA1422-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006781-5	PA1422-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006781-6	PA1422-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006781-7	PA1422-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006781-8	PA1422-FITC	FITC	100 ug	$570		Add to Cart
BHA21006781-9	PA1422-HRP	HRP	100 ug	$570		Add to Cart
BHA21006781-10	PA1422-APC	APC	100 ug	$670		Add to Cart
BHA21006781-11	PA1422-PE	PE	100 ug	$670		Add to Cart
BHA21006781-12	PA1422-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006781-13	PA1422-carrier-free	carrier-free	100 ug	$370		Add to Cart

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